Hemodynamic Changes in Splanchnic Blood Vessels in Portal Hypertension
نویسندگان
چکیده
منابع مشابه
Hemodynamic changes in hypertension.
DESPITE a vast amount of work devoted to the subject the nature of the fundamental hemodynamic changes in chronic, human hypertension is poorly understood. In this necessarily brief discussion the main outlines of the problem will be sketched in emphasizing the respective roles of the heart, large arteries and resistance vessels. Other factors such as the sympathetic nervous system, the barorec...
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Portal hypertension (PHT) is associated with hemodynamic changes in intrahepatic, systemic, and portosystemic collateral circulation. Increased intrahepatic resistance and hyperdynamic circulatory alterations with expansion of collateral circulation play a central role in the pathogenesis of PHT. PHT is also characterized by changes in vascular structure, termed vascular remodeling, which is an...
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We investigated the haemodynamic response to volume depletion and subsequent repletion in patients with cirrhosis and portal hypertension. Twelve patients with compensated cirrhosis and portal hypertension were included in the study. The haemodynamic changes occurring after removal of approx. 15% of the blood volume, and subsequently after isovolume repletion with colloid, were assessed. Baseli...
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Although restricted transhepatic portal flow is necessary for development of generalized portal hypertension (GPH), increased splanchnic arterial inflow also contributes to GPH and its clinical sequelae. In this context, we describe 7 male and 6 female patients (mean age 48 years) in whom the lesser splanchnic (gastrosplenic) system played a key role in the signs and symptoms of GPH. These 13 p...
متن کاملEffect of two models of portal hypertension on splanchnic organ blood flow in the rat.
Splanchnic organ blood flow and cardiac output were measured by the microsphere method in fasted rats with prehepatic portal hypertension due to portal vein stenosis, in rats with intrahepatic portal hypertension due to bile duct ligation, and in unoperated normal rats. Portal venous pressure was higher in both groups of portal hypertensive rats than in normal rats. Cardiac output was significa...
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ژورنال
عنوان ژورنال: The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
سال: 2008
ISSN: 1932-8486,1932-8494
DOI: 10.1002/ar.20667